Pharmacodynamics of the Novel Metallo-β-Lactamase Inhibitor ANT2681 in Combination with meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae

Oct 20, 2020

Shampa Das, Adam Johnson, Laura McEntee, Nicola Farrington, Adam Kirby, Jennifer Unsworth, Ana Jimenez-Valverde, Ruwanthi Kolamunnage-Dona, Justine Bousquet, Laethitia Alibaud, Carole Sable, Magdalena Zalacain, Martin Everett, William Hope

ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae

Aug 4, 2020

David T. Davies, Simon Leiris, Nicolas Sprynski, Jérôme Castandet, Clarisse Lozano, Justine Bousquet, Magdalena Zalacain, Srinivas Vasa, Praveen K. Dasari, Ramesh Pattipati, Naresh Vempala, Swetha Gujjewar, SyamKumar Godi, Raju Jallala, Rajashekar Reddy Sathyap,...

SAR Studies Leading to the Identification of a Novel Series of Metallo-β-Lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model

Nov 18, 2018

Simon Leiris, Alicia Coelho, Jérôme Castandet, Maëlle Bayet, Clarisse Lozano, Juliette Bougnon, Justine Bousquet, Martin Everett, Marc Lemonnier, Nicolas Sprynski, Magdalena Zalacain, Thomas David Pallin, Michael C. Cramp, Neil Jennings, Gilles Raphy, Mark W. Jones,...

Discovery of a Novel Metallo b-Lactamase Inhibitor That Potentiates Meropenem Activity against Carbapenem- Resistant Enterobacteriacea

Apr 18, 2018

Martin Everett, Nicolas Sprynski, Alicia Coelho, Jérôme Castandet, Maëlle Bayet, Juliette Bougnon, Clarisse Lozano, David T. Davies, Simon Leiris, Magdalena Zalacain, Ian Morrissey, Sophie Magnet, Kirsty Holden, Peter Warn, Filomena De Luca, Jean-Denis Docquier, Marc...