Disarming Carbapenemase-Producing Acinetobacter baumannii: High Potency of the Novel Therapeutic Combination of meropenem and the Innovative Diazabicyclooctane β-Lactamase Inhibitor pilabactam (Formerly ANT3310)

Feb 19, 2026

Salud Rodríguez-Pallares, Michelle Outeda-García, Emilio Lence, Arianna Rodríguez-Coello, Lucía González-Pinto, Paula Guijarro-Sánchez, Gabriela A. Báez-Barroso, Tania Blanco-Martín, Juan C. Vázquez-Ucha, Agustina Llanos, Filomena Sannio, Jean-Denis Docquier, Ian...

Meropenem-ANT3310, a Unique β-Lactam-β-Lactamase Inhibitor Combination with Expanded Antibacterial Spectrum Against Gram-Negative Pathogens Including Carbapenem-Resistant Acinetobacter baumannii

Jan 30, 2024

Magdalena Zalacain, Pauline Achard, Agustina Llanos, Ian Morrissey, Stephen Hawser, Kirsty Holden, Eleanor Toomey, David Davies, Simon Leiris, Carole Sable, Adeline Ledoux, Justine Bousquet, Jérôme Castandet, Clarisse Lozano, Martin Everett, Marc Lemonnier.

Higher Levels of Pseudomonas aeruginosa LasB Elastase Expression Are Associated with Early-Stage Infection in Cystic Fibrosis Patients

Aug 30, 2023

Agustina Llanos, Pauline Achard, Justine Bousquet, Clarisse Lozano, Magdalena Zalacain, Carole Sable, Hélène Revillet, Marlène Murris, Marie Mittaine, Marc Lemonnier and Martin Everett.

Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models

Jan 20, 2023

Martin J. Everett, David T. Davies, Simon Leiris, Nicolas Sprynski, Agustina Llanos, Jérôme M. Castandet, Clarisse Lozano, Christopher N. LaRock, Doris L. LaRock, Giuseppina Corsica, Jean-Denis Docquier, Thomas D. Pallin, Andrew Cridland, Toby Blench, Magdalena...

Pseudomonas aeruginosa Elastase (LasB) as a Therapeutic Target

Sep 26, 2021

Martin J Everett, David T Davies